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Histone H3 Monoclonal Antibody(8F7)

Histone H3 Monoclonal Antibody(8F7)

簡要描述:Histone H3 Monoclonal Antibody(8F7)
宿主: Monoclonal, Mouse
反應(yīng)性: Human;Mouse;Rat
應(yīng)用: WB

產(chǎn)品型號: YP-Ab-01128

所屬分類:標(biāo)簽內(nèi)參抗體

更新時間:2024-11-01

詳細(xì)說明:

Histone H3 Monoclonal Antibody(8F7)

抗體,也叫免疫球蛋白(Ig),是一種能特異性結(jié)合抗原的糖蛋白,而抗原是在易感染動物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi),抗體是由于外源性分子的侵襲而產(chǎn)生的??贵w以一個或者多個Y字形單體存在,每個Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū),為抗原結(jié)合部位。任何一個抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構(gòu)上的差異),每一個抗體的重鏈則決定了它的類或型。

產(chǎn)品詳情
The antibody detects endogenous Histone H3 protein.
免疫原詳細(xì)信息
Recombinant Protein of Histone H3
相關(guān)試劑
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
背景

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]


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備注:圖片僅供參考。僅供科研,不可用于臨床。

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